Male-specific metabolism of simvastatin by rat liver microsomes.
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چکیده
منابع مشابه
Digitoxin metabolism by rat liver microsomes.
published by admin on Fri, 03/14/2014 8:53am Title Digitoxin metabolism by rat liver microsomes. Publication Type Journal Article Year of Publication 1975 Authors Schmoldt, A, Benthe, HF, Haberland, G Journal Biochem Pharmacol Volume 24 Issue 17 Pagination 1639-41 Date Published 1975 Sep 1 ISSN 0006-2952
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متن کاملInhibitory effects of amiodarone on simvastatin metabolism in human liver microsomes
Objective To investigate the effects of amiodarone (AMD) on simvastatin (SV) in human liver microsomes and the possible underlying mechanisms. Methods Time-, NADPHand concentration-dependent inhibitions were tested in HLM. The logarithm of relative inhibition values was plotted versus preincubation time (0, 5, 10, 15, 20min) for a series concentration of AMD used (0, 2, 5, 25, 50μmol/L), and th...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1991
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.39.236